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1

Implementation of lean production systems in small and medium-sized pharmaceutical enterprises

Sieckmann, Felix, Ngoc, Hien Nguyen, Helm, René, Kohl, Holger

Journal:

Procedia Manufacturing

Year:

2018

Language:

english

File:

PDF, 861 KB

english, 2018

2

Epitaxial Mn 5 Ge 3 (100) layer on Ge (100) substrates obtained by flash lamp annealing

Xie, Yufang, Yuan, Ye, Wang, Mao, Xu, Chi, Hübner, René, Grenzer, Jörg, Zeng, Yu-Jia, Helm, Manfred, Zhou, Shengqiang, Prucnal, Slawomir

Journal:

Applied Physics Letters

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

3

Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis

Tanja C. A. Tolboom, Annette H. M. van der Helm-Van Mil, Rob G. H. H. Nelissen, Ferdinand C. Breedveld, René E. M. Toes, Tom W. J. Huizinga

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 78 KB

english, 2005

4

An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility

Annette H. M. van der Helm-van Mil, Tom W. J. Huizinga, Geziena M. Th. Schreuder, Ferdinand C. Breedveld, René R. P. de Vries, René E. M. Toes

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 84 KB

english, 2005

5

Association of HLA–DR3 with anti–cyclic citrullinated peptide antibody–negative rheumatoid arthritis

Kirsten N. Verpoort, Floris A. van Gaalen, Annette H. M. van der Helm-van Mil, Geziena M. T. Schreuder, Ferdinand C. Breedveld, Tom W. J. Huizinga, Rene R. P. de Vries, Rene E. M. Toes

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 55 KB

english, 2005

6

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

Annette H. M. van der Helm-van Mil, Kirsten N. Verpoort, Ferdinand C. Breedveld, Tom W. J. Huizinga, René E. M. Toes, René R. P. de Vries

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

7

A prediction rule for disease outcome in patients with Recent-onset undifferentiated arthritis: How to guide individual treatment decisions

Annette H. M. van der Helm-vanMil, Saskia le Cessie, Henrike van Dongen, Ferdinand C. Breedveld, René E. M. Toes, Tom W. J. Huizinga

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 112 KB

english, 2007

8

The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide

Annette H. M. van der Helm-van Mil, Kirsten N. Verpoort, Saskia le Cessie, Tom W. J. Huizinga, René R. P. de Vries, René E. M. Toes

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 83 KB

english, 2007

9

Emerging patterns of risk factor make-up enable subclassification of rheumatoid arthritis

Annette H. M. van der Helm-van Mil, Tom W. J. Huizinga, René R. P. de Vries, René E. M. Toes

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 152 KB

english, 2007

10

The inflammatory disease–associated variants in IL12B and IL23R are not associated with rheumatoid arthritis

Monica Chang, Randall K. Saiki, Joseph J. Cantanese, David Lew, Annette H. M. van der Helm-van Mil, Rene E. M. Toes, Thomas W. J. Huizinga, Kristin G. Ardlie, Lindsey A. Criswell, Michael F. Seldin, C

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

11

Genome-wide single-nucleotide polymorphism studies in rheumatology: Hype or hope?

Annette H. M. van der Helm-van Mil, Leonid Padyukov, René E. M. Toes, Lars Klareskog, Tom W. J. Huizinga

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

12

Quantitative heritability of anti–citrullinated protein antibody–positive and anti–citrullinated protein antibody–negative rheumatoid arthritis

Diane van der Woude, Jeanine J. Houwing-Duistermaat, René E. M. Toes, Tom W. J. Huizinga, Wendy Thomson, Jane Worthington, Annette H. M. van der Helm-van Mil, René R. P. de Vries

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

13

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug–free remission in rheumatoid arthritis: Results from two large early arthritis cohorts

Diane van der Woude, Adam Young, Keeranur Jayakumar, Bart J. Mertens, René E. M. Toes, Désirée van der Heijde, Tom W. J. Huizinga, Annette H. M. van der Helm-van Mil

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 96 KB

english, 2009

14

Value of anti–modified citrullinated vimentin and third-generation anti–cyclic citrullinated peptide compared with second-generation anti–cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis

Michael P. M. van der Linden, Diane van der Woude, Andreea Ioan-Facsinay, E. W. Nivine Levarht, Gerrie Stoeken-Rijsbergen, Tom W. J. Huizinga, René E. M. Toes, Annette H. M. van der Helm-van Mil

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

15

Identification of CXCL13 as a marker for rheumatoid arthritis outcome using an in silico model of the rheumatic joint

Cees M. Meeuwisse, Michael P. van der Linden, Ton A. Rullmann, Cornelia F. Allaart, Rob Nelissen, Tom W. Huizinga, Anja Garritsen, René E. Toes, René van Schaik, Annette H. van der Helm-van Mil

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

16

Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis

Inge R. Klein-Wieringa, Michael P. M. van der Linden, Rachel Knevel, Joanneke C. Kwekkeboom, Els van Beelen, Tom W. J. Huizinga, Annette van der Helm-van Mil, Margreet Kloppenburg, René E. M. Toes, An

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 179 KB

english, 2011

17

Soluble factors released by ATDC5 cells affect the formation of calcium phosphate crystals

Leonie F.A. Huitema, P. René van Weeren, Bas W.M. van Balkom, Tom Visser, Chris H.A. van de Lest, Ab Barneveld, J. Bernd Helms, Arie B. Vaandrager

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2007

Language:

english

File:

PDF, 1.05 MB

english, 2007

18

Novel scoring function for modeling structures of oligomers of transmembrane α-helices

Yungki Park, Markus Elsner, Rene Staritzbichler, Volkhard Helms

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2004

Language:

english

File:

PDF, 437 KB

english, 2004

19

A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold

Helms, Larry R., DesJarlais, Renee L., Abdel-Meguid, Sherin S., Wetzel, Ronald, Zhao, Baoguang

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 773 KB

1995

20

Collagenous spherulosis in an oral mucous cyst

Cathy Renee Henry, Mindy Nace, Klaus F. Helm

Journal:

Journal of Cutaneous Pathology

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

21

Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization

Leonie F.A. Huitema, P. René van Weeren, Ab Barneveld, Chris H.A. van de Lest, J. Bernd Helms, Arie B. Vaandrager

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

22

Scaffold design and optimization: the use of endothelial progenitor cells in vitro and in vivo

Jacqueline Alblas, Ruth Geuze, Natalja Fedorovich, Diyar Delawi, Yvonne van der Helm, Rene Haverslag, Fiona Wegman, Daphne van Geemen, Ab Verbout, Wouter Dhert

Journal:

Year:

2008

Language:

english

File:

PDF, 88 KB

english, 2008

23

Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis

Henrik Källberg, Leonid Padyukov, Robert M. Plenge, Johan Rönnelid, Peter K. Gregersen, Annette H.M. van der Helm-van Mil, Rene E.M. Toes, Tom W. Huizinga, Lars Klareskog, Lars Alfredsson

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 331 KB

english, 2007

24

Soy immunotherapy for peanut-allergic mice: Modulation of the peanut-allergic response

Pons, Laurent, Ponnappan, Usha, Hall, Renée A., Simpson, Pippa, Cockrell, Gael, West, C. Michael, Sampson, Hugh A., Helm, Ricki M., Burks, A. Wesley

Journal:

Journal of Allergy and Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

25

thin film observed with terahertz spectroscopy

Jepsen, Peter Uhd, Fischer, Bernd M., Thoman, Andreas, Helm, Hanspeter, Suh, J. Y., Lopez, René, Haglund, R. F.

Journal:

Physical Review B

Year:

2006

Language:

english

File:

PDF, 550 KB

english, 2006

26

Are Solvation Free Energies of Homogeneous Helical Peptides Additive?

Staritzbichler, René, Gu, Wei, Helms, Volkhard

Journal:

Journal of Physical Chemistry B

Year:

2005

Language:

english

File:

PDF, 232 KB

english, 2005

27

Forming-Free Resistive Switching in Multiferroic BiFeO 3 thin Films with Enhanced Nanoscale Shunts

Ou, Xin, Shuai, Yao, Luo, Wenbo, Siles, Pablo F., Kögler, Reinhard, Fiedler, Jan, Reuther, Helfried, Zhou, Shengqiang, Hübner, René, Facsko, Stefan, Helm, Manfred, Mikolajick, Thomas, Schmidt, Oliver

Journal:

ACS Applied Materials & Interfaces

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

28

Profiling of RNA modifications by multiplexed stable isotope labelling

Kellner, Stefanie, Neumann, Jennifer, Rosenkranz, David, Lebedeva, Svetlana, Ketting, René F., Zischler, Hans, Schneider, Dirk, Helm, Mark

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

29

Metal-Insulator Phase Transition in VO2: A Look from the Far Infrared Side

Jepsen, Peter Uhd, Fischer, Bernd M., Thoman, Andreas, Helm, Hanspeter, Suh, J. Y., Lopez, Rene, Hanglund, Richard F.

Journal:

MRS Proceedings

Year:

2006

Language:

english

File:

PDF, 588 KB

english, 2006

30

Learning Factories for Sustainable Manufacturing - A Generic Design Approach

Helm, René, Reise, Carsten, Rößle, Dominik

Journal:

Advanced Materials Research

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

31

Integrated simulation of drinking water treatment

Rietveld, Luuk, van Dijk, Hans, van der Helm, Alex, van Schagen, Kim, van der Aa, René

Journal:

Journal of Water Supply: Research and Technology-AQUA Online

Year:

2008

Language:

english

File:

PDF, 273 KB

english, 2008

32

Liquid phase epitaxy of binary III–V nanocrystals in thin Si layers triggered by ion implantation and flash lamp annealing

Wutzler, Rene, Rebohle, Lars, Prucnal, Slawomir, Bregolin, Felipe L., Hübner, Rene, Voelskow, Matthias, Helm, Manfred, Skorupa, Wolfgang

Journal:

Journal of Applied Physics

Year:

2015

Language:

english

File:

PDF, 2.42 MB

english, 2015

33

Faceted nanostructure arrays with extreme regularity by self-assembly of vacancies

Ou, Xin, Heinig, Karl-Heinz, Hübner, René, Grenzer, Joerg, Wang, Xi, Helm, Manfred, Fassbender, Jürgen, Facsko, Stefan

Journal:

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015

34

Letters

Mary F. Woody, Mari Wirfs Abernathy, Olove Colcord, Gary Ramsey, Donna M. Wing, Kathy Szidon, Betty J. Tucker, Joyce Barrier, Renée Lieb, Donna Waddell, Patricia Hassid, Janet Brown, Barbara Helms, Re

Journal:

AJN American Journal of Nursing

Year:

1976

Language:

english

File:

PDF, 2.24 MB

english, 1976

35

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA

van Heemst, Jurgen, Hensvold, Aase H, Jiang, Xia, van Steenbergen, Hanna, Klareskog, Lars, Huizinga, Tom W J, van der Helm-van Mil, Annette, Catrina, Anca I, Toes, René E M, Lundberg, Karin, van der W

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 660 KB

english, 2015

36

Ferromagnetic Mn-implanted GaP: Microstructures vs. magnetic properties

Yuan, Ye, Huebner, Rene, Liu, Fang, Sawicki, Maciej, Gordan, Ovidiu D., Salvan, Georgeta, Zahn, Dietrich R. T., Banerjee, Dipanjan, Bähtz, Carsten, Helm, Manfred, Zhou, Shengqiang

Journal:

ACS Applied Materials & Interfaces

Year:

2016

Language:

english

File:

PDF, 6.52 MB

english, 2016

37

Timing-based business models for flexibility creation in the electric power sector

Helms, Thorsten, Loock, Moritz, Bohnsack, René

Journal:

Year:

2016

Language:

english

File:

PDF, 686 KB

english, 2016

38

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis

Shi, Jing, van Steenbergen, Hanna W., van Nies, Jessica A. B., Levarht, E. W. Nivine, Huizinga, Tom W. J., van der Helm-van Mil, Annette H. M., Toes, René E. M., Trouw, Leendert A.

Journal:

Arthritis Research & Therapy

Year:

2015

Language:

english

File:

PDF, 548 KB

english, 2015

39

Droplet-confined alternate pulsed epitaxy of GaAs nanowires on Si substrates down to CMOS-compatible temperatures

Dimakis, Emmanouil, Balaghi, Leila, Tauchnitz, Tina, Huebner, Rene, Bischoff, Lothar, Schneider, Harald, Helm, Manfred

Journal:

Year:

2016

Language:

english

File:

PDF, 7.65 MB

english, 2016

40

Defect-induced magnetism in SiC: Interplay between ferromagnetism and paramagnetism

Wang, Yutian, Liu, Yu, Wendler, Elke, Hübner, René, Anwand, Wolfgang, Wang, Gang, Chen, Xuliang, Tong, Wei, Yang, Zhaorong, Munnik, Frans, Bukalis, Gregor, Chen, Xiaolong, Gemming, Sibylle, Helm, Manf

Journal:

Physical Review B

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

41

Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers

Hersom, Maria, Helms, Hans Christian, Pretzer, Natasia, Goldeman, Charlotte, Jensen, Andreas I., Severin, Gregory, Nielsen, Morten S., Holm, René, Brodin, Birger

Journal:

Molecular and Cellular Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

42

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation

Brummelman, Jolanda, Raeven, René H. M., Helm, Kina, Pennings, Jeroen L. A., Metz, Bernard, van Eden, Willem, van Els, Cécile A. C. M., Han, Wanda G. H.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.06 MB

english, 2016

43

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF

Boeters, Debbie M., Nieuwenhuis, Wouter P., Verheul, Marije K., Newsum, Elize C., Reijnierse, Monique, Toes, René E. M., Trouw, Leendert A., van der Helm-van Mil, Annette H. M.

Journal:

Arthritis Research & Therapy

Year:

2016

Language:

english

File:

PDF, 988 KB

english, 2016

44

Rapid frequency-dependent changes in free mitochondrial calcium concentration in rat cardiac myocytes

Wüst, Rob C. I., Helmes, Michiel, Martin, Jody L., van der Wardt, Thomas J. T., Musters, René J. P., van der Velden, Jolanda, Stienen, Ger J. M.

Journal:

The Journal of Physiology

Year:

2017

Language:

english

File:

PDF, 2.05 MB

english, 2017

45

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine

Raeven, René H. M., Brummelman, Jolanda, Pennings, Jeroen L. A., van der Maas, Larissa, Tilstra, Wichard, Helm, Kina, van Riet, Elly, Jiskoot, Wim, van Els, Cécile A. C. M., Han, Wanda G. H., Kersten,

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

46

Room-temperature short-wavelength infrared Si photodetector

Berencén, Yonder, Prucnal, Slawomir, Liu, Fang, Skorupa, Ilona, Hübner, René, Rebohle, Lars, Zhou, Shengqiang, Schneider, Harald, Helm, Manfred, Skorupa, Wolfgang

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

47

Realizing the insulator-to-metal transition in Se-hyperdoped Si via non-equilibrium material processing

Liu, Fang, Prucnal, Slawomir, Berencén, Yonder, Zhang, Zhi Tao, Yuan, Ye, Liu, Yu, Heller, René, Boettger, Roman, Rebohle, Lars, Skorupa, Wolfgang, Helm, Manfred, Zhou, Shengqiang

Journal:

Journal of Physics D Applied Physics

Year:

2017

Language:

english

File:

PDF, 684 KB

english, 2017

48

In-situ ohmic contact formation for n-type Ge via non-equilibrium processing

Prucnal, Slawomir, Frigerio, Jacopo, Napolitani, Enrico, Ballabio, Andrea, Berencén, Yonder, Rebohle, Lars, Wang, Mao, Boettger, Roman, Voelskow, Matthias, Isella, Giovanni, Hübner, René, Helm, Manfre

Journal:

Semiconductor Science and Technology

Year:

2017

Language:

english

File:

PDF, 1021 KB

english, 2017

49

Decoupling the two roles of Ga droplets in the self-catalyzed growth of GaAs nanowires on SiO x /Si substrates

Tauchnitz, Tina, Nurmamytov, Timur, Hübner, René, Engler, Martin, Facsko, Stefan, Schneider, Harald, Helm, Manfred, Dimakis, Emmanouil

Journal:

Crystal Growth & Design

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

50

The risk of individual autoantibodies, autoantibody combinations and levels for arthritis development in clinically suspect arthralgia

ten Brinck, Robin M., van Steenbergen, Hanna W., van Delft, Myrthe A. M., Verheul, Marije K., Toes, Rene E. M., Trouw, Leendert A., van der Helm – van Mil, Annette H. M.

Journal:

Year:

2017

Language:

english

File:

PDF, 323 KB

english, 2017